Hope for Age-Related Ovarian Decline? Exploring New Approaches
While ovarian function naturally declines with age, recent research explores promising new directions. Studies have identified two types of germline stem cells, “female germ stem cells” (fGSC) or “ovarian stem cells” (OSCs), that may hold the key to ovarian regeneration and sustained function.
Alternative Approaches for Ovarian Function:
Cell-Based Therapies: Research is investigating the potential of using a patient’s own cells (possibly from bone marrow) to stimulate ovarian function. This could potentially restore hormone levels and even fertility.
Stimulating Ovarian Reserve: Early evidence suggests that these cell-based approaches may improve ovarian reserve function by increasing the number of follicles (egg sacs) while decreasing FSH (Follicle Stimulating Hormone) levels and increasing AMH (Anti-Müllerian Hormone) and E2 (Estradiol) levels.
Promoting Ovarian Health: Studies are examining the possibility of using these cells to increase ovarian weight, enhance hormone production, and stimulate the development of follicles.
Overall, this research suggests that cell-based therapies offer a potential future direction for treating female infertility by promoting ovarian health and potentially even menstrual function.
Any patient can take advantage of laser-assisted hatching, but those most likely to be best suited are those who:
» Are above the age of 37
» Produce a high level of Follicle
» Stimulating Hormone (FSH) early in their cycle
» Have had unsuccessful IVF cycles
» Have a tendency to produce a harder and/or thicker zona pellucida
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